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Four days of brain stimulation improved memory for a month

Memory decline is often treated as a one-way slide once a person reaches their sixties or seventies.

Crescent Bioresearch6 April, 7:19 AMGrover et al., Nature Neuroscience, 2022 · Boston University2 min read

Researchers at Boston University applied a mild, non-invasive electrical current to the scalp of older adults for 20 minutes a day across four consecutive days, targeting brain regions tied to two different kinds of memory, and tested recall afterward.

Stimulating the parietal cortex at a low frequency improved working memory, the ability to briefly hold and manipulate information, while stimulating the prefrontal cortex at a higher frequency improved long-term memory recall instead. Adults aged 65 to 88 who started with weaker memory showed the largest and most durable gains.

Both improvements were still measurable a full month after the four-day stimulation ended, well beyond the treatment window itself, suggesting the brain's underlying plasticity had genuinely shifted rather than producing a brief, temporary boost. The device used mild alternating current through the scalp, not surgery, though the long-term safety of repeated sessions and whether gains persist beyond a month are still being studied.

Crescent Discovery Series cover: Four days of brain stimulation improved memory for a month

Four days of current, a month of better memory.

Source

  1. Grover, S., Wen, W., Viswanathan, V., Gill, C. T., & Reinhart, R. M. G. (2022). Long-lasting, dissociable improvements in working memory and long-term memory in older adults with repetitive neuromodulation. Nature Neuroscience, 25(9), 1237–1246. https://doi.org/10.1038/s41593-022-01132-3
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