Crescent Discovery Series

A reading room for breakthroughs and the curious mind

Every extra 10cm of height adds 10 percent more cancer risk

Taller people are diagnosed with cancer more often than shorter people, across dozens of studies and countries.

Crescent Bioresearch23 July, 7:54 AMNunney, Proceedings of the Royal Society B, 2018 · University of California, Riverside2 min read

Leonard Nunney at the University of California, Riverside analyzed height and cancer data across 23 different cancer types, drawn from four large population surveillance projects, to test a simple explanation: more height means more cells, and more cells means more chances for one of them to turn cancerous.

Overall, each additional 10 centimeters of height was associated with about a 10 percent increase in cancer risk, and most cancer types closely matched what pure cell-number math would predict. Melanoma was an exception, showing a far stronger link to height than cell count alone could explain, which pointed to some additional mechanism at work.

Cancer risks tied to obesity did not track the height effects, which argued against body size in general being the driver and supported cell number as the mechanism for most cancer types. The analysis cannot say anything about an individual person's risk, since countless other factors matter more, but it helps explain why height is a modest, consistent cancer risk factor across populations.

Crescent Discovery Series cover: Every extra 10cm of height adds 10 percent more cancer risk

Taller bodies, more cells, slightly more risk.

Source

  1. Nunney, L. (2018). Size matters: height, cell number and a person's risk of cancer. Proceedings Biological Sciences, 285(1889). https://doi.org/10.1098/rspb.2018.1743
Crescent Discovery Series

Follow the series

New discoveries are published on our channels every day.

Keep going

Three more numbers