Crescent Discovery Series

A reading room for breakthroughs and the curious mind

Hearing care slowed decline only in the higher-risk group

A large trial set out to test something most doctors assumed but had never proven: that treating hearing loss protects thinking skills.

Crescent Bioresearch16 August, 9:54 AMLin et al., The Lancet, 2023 · Johns Hopkins Bloomberg School of Public Health2 min read

Researchers led by the Johns Hopkins Bloomberg School of Public Health randomly assigned nearly 1,000 older adults with hearing loss to either hearing aids or a health education program, then tracked their cognitive test scores for three years.

Across the full study group, hearing aids made no measurable difference in three-year cognitive decline. But in a prespecified comparison, among older, higher-risk adults drawn from an established heart-health cohort, hearing aid use slowed cognitive decline by about 48 percent compared with the control group.

The split result came from combining two groups of volunteers in one trial: a healthier group that sought out the study on its own, which showed no benefit, and an older, higher-risk group recruited from a long-running cardiovascular study, which showed a large one. Researchers now want to identify in advance which patients most resemble the second group.

Crescent Discovery Series cover: Hearing care slowed decline only in the higher-risk group

One hearing aid trial, two very different results.

Source

  1. Lin, F. R., Pike, J. R., Albert, M. S., Arnold, M., Burgard, S., Chisolm, T., Couper, D., Deal, J. A., Goman, A. M., Glynn, N. W., Gmelin, T., Gravens-Mueller, L., Hayden, K. M., Huang, A. R., Knopman, D., Mitchell, C. M., Mosley, T., Pankow, J. S., Reed, N. S., . . . ACHIEVE Collaborative Research Group (2023). Hearing intervention versus health education control to reduce cognitive decline in older adults with hearing loss in the USA (ACHIEVE): a multicentre, randomised controlled trial. The Lancet, 402(10404), 786–797. https://doi.org/10.1016/S0140-6736(23)01406-X
Crescent Discovery Series

Follow the series

New discoveries are published on our channels every day.

Keep going

Three more numbers