Crescent Discovery Series

A reading room for breakthroughs and the curious mind

Cataract surgery was linked to 29 percent less dementia

For years, clouded vision in old age was treated as separate from the slow decline of memory and thinking.

Crescent Bioresearch13 October, 1:16 PMLee et al., JAMA Internal Medicine, 2021 · University of Washington2 min read

Researchers running a long-term Seattle study called Adult Changes in Thought followed thousands of older adults for years, tracking who developed cataracts, who had them removed, and who later developed dementia.

Among 3,038 participants with cataract or glaucoma, Cecilia Lee's team at the University of Washington found that those who had cataract surgery were about 29 percent less likely to be diagnosed with dementia than those who did not, a gap that held after adjusting for health and education. Removing cloudy lenses from the eyes, not the surgery itself, seemed to matter.

As a check, the researchers looked at glaucoma surgery, which did not lower dementia risk, suggesting clearer vision itself, not contact with the health system, explained the pattern. Still, this was an observational study, not a randomized trial. People who get cataract surgery may simply be healthier to begin with, so the link is a strong association, not proof of cause.

Crescent Discovery Series cover: Cataract surgery was linked to 29 percent less dementia

An association, not yet a cause.

Source

  1. Lee, C. S., Gibbons, L. E., Lee, A. Y., Yanagihara, R. T., Blazes, M. S., Lee, M. L., McCurry, S. M., Bowen, J. D., McCormick, W. C., Crane, P. K., & Larson, E. B. (2022). Association Between Cataract Extraction and Development of Dementia. JAMA Internal Medicine, 182(2), 134–141. https://doi.org/10.1001/jamainternmed.2021.6990
Crescent Discovery Series

Follow the series

New discoveries are published on our channels every day.

Keep going

Three more numbers