Doctors ordered a brain scan expecting something minor. Instead it showed fluid-filled chambers so enlarged that his brain tissue was pressed into a thin shell against the skull. As a baby he had been treated for hydrocephalus, a buildup of the fluid, with a drainage shunt.
The scans showed massive enlargement of the fluid-filled ventricles, with the brain itself reduced to a thin mantle. Yet he was married, had two children, and worked as a civil servant. His IQ tested at 75, below average, while he lived an ordinary working life.
His case became one of the most cited illustrations of the brain's capacity to reorganize around profound structural loss, since the compression appears to have built up slowly over decades rather than suddenly. It remains a single documented case, not a trial, and doctors still cannot say how much of ordinary brain anatomy is truly load-bearing versus redundant.

Read the original study
Feuillet, Dufour and Pelletier, The Lancet, 2007 · doi.org/10.1016/S0140-6736(07)61127-1
Rewritten by millimeters, for forty years.
Source
- Feuillet, L., Dufour, H., & Pelletier, J. (2007). Brain of a white-collar worker. The Lancet, 370(9583), 262. https://doi.org/10.1016/S0140-6736(07)61127-1